{"id":19,"date":"2007-09-20T10:53:34","date_gmt":"2007-09-20T10:53:34","guid":{"rendered":"http:\/\/astraea.net\/blog\/?p=19"},"modified":"2007-09-20T10:53:34","modified_gmt":"2007-09-20T10:53:34","slug":"modest-eating-red-wine-and-longevity","status":"publish","type":"post","link":"https:\/\/www.astraea.net\/blog\/modest-eating-red-wine-and-longevity\/","title":{"rendered":"Modest eating, red wine and longevity"},"content":{"rendered":"<p>So long as there is adequate nutrition, cutting    calories by 40pc prolongs lifespan by 50pc or more &#8212; in yeast, mice, rats    and every other species so far tested.<\/p>\n<p>In 1999 David Sinclair, at Harvard, showed that a single gene, SIRT1,    controlled the process of ageing. Subsequent work showed that resveratrol, found in red wine, activates    this gene.\u00a0 Perhaps this explains why red wine seems to prolong healthy life.<\/p>\n<p>Animal evidence suggests that it should work against the developed world&#8217;s    fastest-growing degenerative disease, diabetes.<\/p>\n<p>Now a small trial in Newcastle-upon-Tyne, in north-east England, will test    resveratrol, which could lead to a whole family of new drugs with    powerful effects against the diseases of ageing.\u00a0 Also, a proprietary version of resveratrol, SRT501, is under trial in India    against diabetes, and newer versions, hundreds of times more powerful, are    in the pipeline.<\/p>\n<p>Personally, I&#8217;d rather eat a bit less (its cheaper and frees up time for doing other things) and have a occasional glass of red, rather than have to resort to a chemical pipeline.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>So long as there is adequate nutrition, cutting calories by 40pc prolongs lifespan by 50pc or more &#8212; in yeast, mice, rats and every other species so far tested. In 1999 David Sinclair, at Harvard, showed that a single gene, SIRT1, controlled the process of ageing. Subsequent work showed that resveratrol, found in red wine, &hellip;<br \/><a href=\"https:\/\/www.astraea.net\/blog\/modest-eating-red-wine-and-longevity\/\" class=\"more-link pen_button pen_element_default pen_icon_arrow_double\">Continue reading <span class=\"screen-reader-text\">Modest eating, red wine and longevity<\/span><\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"jetpack_post_was_ever_published":false,"footnotes":"","jetpack_publicize_message":"","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":false,"jetpack_social_options":{"image_generator_settings":{"template":"highway","default_image_id":0,"font":"","enabled":false},"version":2}},"categories":[13],"tags":[],"class_list":["post-19","post","type-post","status-publish","format-standard","hentry","category-health"],"jetpack_publicize_connections":[],"jetpack_featured_media_url":"","jetpack_sharing_enabled":true,"jetpack_shortlink":"https:\/\/wp.me\/p4hwcd-j","jetpack_likes_enabled":true,"_links":{"self":[{"href":"https:\/\/www.astraea.net\/blog\/wp-json\/wp\/v2\/posts\/19","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.astraea.net\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.astraea.net\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.astraea.net\/blog\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.astraea.net\/blog\/wp-json\/wp\/v2\/comments?post=19"}],"version-history":[{"count":0,"href":"https:\/\/www.astraea.net\/blog\/wp-json\/wp\/v2\/posts\/19\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.astraea.net\/blog\/wp-json\/wp\/v2\/media?parent=19"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.astraea.net\/blog\/wp-json\/wp\/v2\/categories?post=19"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.astraea.net\/blog\/wp-json\/wp\/v2\/tags?post=19"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}